Spectroscopy Standards
Cayman Chemical JWH 145 Analytical Reference S
A (1-naphthoyl)pyrrole analog of JWH 018 that potently activates both CB1 and CB2 receptors (Ki values of 14 and 6.4 nM, respectively); intended for forensic and research applications
Cayman Chemical 5 6EETd11 GC MS Standards
An internal standard for the quantification of 5(6)-EET by GC- or LC-MS
Medchemexpress LLC Substance P | 33507-63-0 | >99.6% | 1347.63 | 5 MG
Substance P (Neurokinin P) is a CNS-penetrant neuropeptide that functions as both a neurotransmitter and a neuromodulator in the central nervous system. Its endogenous receptor is the neurokinin 1 receptor (NK1-receptor, NK1R).
- CNS-penetrant neuropeptide
- Acts as a neurotransmitter and neuromodulator in the CNS
- Endogenous receptor is neurokinin 1 receptor (NK1R)
- Available in multiple package sizes
- High purity of 99.6%
Apexbio Technology LLC Annexin V-Cy3/SYTOX Green Apoptosis Kit 100assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds phosphatidylserine (PS) PS is normally located on the inner leaflet of the cell membrane lipid bilayer but flips from the inner to the outer leaflet during the early stages of apoptosis becoming exposed to the extracellular environment Annexin V has a high affinity for PS By conjugating Annexin V with Cy3 the labeled Annexin V serves as a fluorescent probe enabling detection of apoptosis events via flow cytometry or fluorescence microscopy within only 10 20 minutes staining SYTOX Green is a membrane-impermeable cyanine dye that normally cannot penetrate intact cell membranes However during late-stage apoptosis or necrosis SYTOX Green can cross disrupted regions of the cell membrane reach the nucleus and bind DNA double helix molecules forming SYTOX Green-DNA complexes Binding increases fluorescence intensity over 500-fold generating bright green fluorescence Thus SYTOX Green stains o
Apexbio Technology LLC Annexin V-FITC/7-AAD Apoptosis Kit 100assays
Annexin V is a calcium-dependent phospholipid-binding protein that specifically binds phosphatidylserine (PS) Normally PS is localized to the inner leaflet of the cell membrane lipid bilayer but during early stages of apoptosis PS flips from the inner leaflet to the outer surface of the plasma membrane where it is exposed to the extracellular environment Annexin V displays a high affinity for PS Fluorescein (FITC)-conjugated Annexin V can be used as a fluorescent probe in flow cytometry or fluorescent microscopy to detect apoptosis within 10-20 minutes The nuclear dye 7-Aminoactinomycin D (7-AAD) specifically binds to double-stranded DNA and fluoresces upon binding Under normal circumstances 7-AAD is cell-impermeable however in late apoptotic and dead cells 7-AAD can pass through cell membranes staining DNA Combining Annexin V-FITC with 7-AAD staining cells at different stages of apoptosis and dead cells can be distinguished effectively
Apexbio Technology LLC One-step TUNEL FITC Apoptosis Detection Kit 100rxns
One-step TUNEL FITC Apoptosis Detection Kit can be used to detect nuclear DNA fragmentation in tissues or cells undergoing apoptosis During apoptosis intracellular DNA endonucleases become activated cleaving genomic DNA between nucleosomes into 180-200 bp fragments or multiples thereof The resulting 3 -OH DNA ends are labeled with tagged dUTP through the catalytic action of Terminal Deoxynucleotidyl Transferase (TdT) allowing detection via fluorescence microscopy or flow cytometry with excitation/emission wavelengths at Ex/Em 492 nm/517 nm This kit has broad application and can be used to detect apoptosis in frozen or paraffin-embedded tissue sections as well as in cultured adherent or suspension cells
Apexbio Technology LLC Annexin V-HF647/7-AAD Apoptosis Kit 100assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (HF647) can be used as a probe in combination with flow cytometry or fluorescence microscopy for detecting apoptosis and the staining process requires only 10-20 minutes 7-AAD specifically binds double-stranded DNA emitting red fluorescence Normally 7-AAD cannot penetrate intact cell membranes However in late-apoptotic and dead cells membrane integrity is compromised allowing 7-AAD to enter and stain nuclear DNA Co-staining with Annexin V-HF647 and 7-AAD thus differentiates cells in various apoptotic stages and dead cells
Apexbio Technology LLC Annexin V-HF488/PI Apoptosis Kit 100assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (HF488) can be used as a fluorescent probe to detect apoptotic cells through flow cytometry or fluorescence microscopy with staining taking only 10-20 minutes Propidium iodide (PI) selectively binds double-stranded DNA and yields a red fluorescence PI is membrane-impermeable in healthy cells but can penetrate the membranes of late apoptotic and dead cells staining their nuclei Simultaneous staining with Annexin V-HF488 and PI enables differentiation between early apoptotic late apoptotic and dead cells
Cayman Chemical Digoxind3 GC MS Standards
An internal standard for the quantification of digoxin by GC- or LC-MS
Cayman Chemical 13 14dihydro15keto Prostaglan
An internal standard for the quantification of 13,14-dihydro-15-keto PGE2 by GC- or LC-MS
Cayman Chemical JWH 015d7 GC MS Standards
An internal standard for the quantification of JWN 015 by GC- or LC-MS; intended for research and forensic applications
![eMolecules AbaChemScene / 2-Bromo-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethan-1-one / 1g / 391085276 / CS-M2583 / 0.000 / 62932-94-9 / MFCD18976157 / 245.072 / C9H9BrO3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502518626.JPG-250.jpg)
eMolecules AbaChemScene / 2-Bromo-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethan-1-one / 1g / 391085276 / CS-M2583 / 0.000 / 62932-94-9 / MFCD18976157 / 245.072 / C9H9BrO3
AbaChemScene / 2-Bromo-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethan-1-one / 1g / 391085276 / CS-M2583 / 0.000 / 62932-94-9 / MFCD18976157 / 245.072 / C9H9BrO3
Cambridge Isotope Laboratories Modified JIS PCB Alt B Calibration Solutions (CS1H-CS5H) 5 x 0 2 mL
Modified JIS PCB Alt B Calibration Solutions (CS1H-CS5H) 5 x 0 2 mL
